feel faint, very dizzy, confused, or have unusual symptoms.become very drowsy with slowed breathing.Get emergency medical help right away if you take opioids and you: This can lead to serious injury, coma, or death. Do not take large amounts of opioids, including opioid-containing medicines, such as heroin or prescription pain pills, to try to overcome the opioid-blocking effects of naltrexone. If you have a seizure while taking CONTRAVE, stop taking CONTRAVE and call your healthcare provider right away. Do not take any other medicines while you are taking CONTRAVE unless your healthcare provider has said it is okay to take them. The risk of seizure is higher in people who take higher doses of CONTRAVE, have certain medical conditions, or take CONTRAVE with certain other medicines. There is a risk of having a seizure when you take CONTRAVE. ![]() Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.ĬONTRAVE may cause serious side effects, including: Tell your healthcare provider about all of your medical conditions including if you have: depression or other mental illnesses attempted suicide seizures head injury tumor or infection of brain or spine low blood sugar or low sodium liver or kidney problems high blood pressure heart attack, heart problems, or stroke eating disorder drinking a lot of alcohol prescription medicine or street drug abuse are 65 or older diabetes pregnant or planning to become pregnant or breastfeeding. ![]() Stop taking CONTRAVE and call a healthcare provider right away if you or your family members notice any of the following symptoms, especially if they are new, worse, or worry you: thoughts about suicide or dying attempts to commit suicide depression anxiety feeling agitated or restless panic attacks irritability aggression, anger, or violence acting on dangerous impulses an extreme increase in activity and talking other unusual changes in behavior or mood trouble sleeping.ĬONTRAVE is not approved for use in children under the age of 18.ĭo not take CONTRAVE if you have uncontrolled high blood pressure have or have had seizures use other medicines that contain bupropion such as WELLBUTRIN, WELLBUTRIN SR, WELLBUTRIN XL, APLENZIN and ZYBAN have or have had an eating disorder called anorexia or bulimia are dependent on opioid pain medicines or use medicines to help stop taking opioids, or are in opiate withdrawal drink a lot of alcohol and abruptly stop drinking, or use medicines called sedatives (these make you sleepy), benzodiazepines, or anti‐seizure medicines and stop using them all of a sudden are taking or have taken medicines called monoamine oxidase inhibitors (MAOIs) in the past 14 days or are allergic to any of the ingredients in CONTRAVE. This is very important when you start taking CONTRAVE or when your dose changes. While taking CONTRAVE, you or your family members should pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. ![]() If you already have depression or other mental illnesses, taking bupropion may cause it to get worse, especially within the first few months of treatment. Bupropion may increase the risk of suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment. ![]() Bupropion has caused some people to have suicidal thoughts or actions or unusual changes in behavior, whether or not they are taking medicines used to treat depression. Suicidal thoughts or actions: One of the ingredients in CONTRAVE is bupropion. CONTRAVE can cause serious side effects including:
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